This photo released by the Syrian official news agency SANA, shows smoke rising from burned cars after a huge explosion shook the Sabaa Bahrat Square, one of the capital's biggest roundabouts, in Damascus, Syria, Monday, April. 8, 2013. A car bomb rocked a busy residential and commercial district in central Damascus on Monday, killing more than a dozen with many more injured and sending a huge cloud of black smoke billowing over the capital?s skyline, Syrian state-run media said. (AP Photo/SANA)
This photo released by the Syrian official news agency SANA, shows smoke rising from burned cars after a huge explosion shook the Sabaa Bahrat Square, one of the capital's biggest roundabouts, in Damascus, Syria, Monday, April. 8, 2013. A car bomb rocked a busy residential and commercial district in central Damascus on Monday, killing more than a dozen with many more injured and sending a huge cloud of black smoke billowing over the capital?s skyline, Syrian state-run media said. (AP Photo/SANA)
This photo released by the Syrian official news agency SANA, shows a Syrian fire fighter extinguishing a burning car after a huge explosion shook the Sabaa Bahrat Square, one of the capital's biggest roundabouts, in Damascus, Syria, Monday, April. 8, 2013. A car bomb rocked a busy residential and commercial district in central Damascus, killing at least a dozen people with more than fifty injured and causing heavy material damage, a Syrian government official said. (AP Photo/SANA)
This photo released by the Syrian official news agency SANA, shows Syrian fire fighters extinguishing burning cars after huge explosion shook the Sabaa Bahrat Square, one of the capital's biggest roundabouts, in Damascus, Syria, Monday, April. 8, 2013. A car bomb rocked a busy residential and commercial district in central Damascus, killing at least a dozen people with tens more injured and causing heavy material damage, a Syrian government official said. (AP Photo/SANA)
This photo released by the Syrian official news agency SANA, shows Syrians inspecting a damaged car at the scene of a car bomb attack near the Sabaa Bahrat Square, one of the capital's biggest roundabouts, in Damascus, Syria, Monday, April. 8, 2013. A car bomb rocked a busy residential and commercial district in central Damascus, killing at least a dozen people with tens more injured and causing heavy material damage, a Syrian government official said. (AP Photo/SANA)
This photo released by the Syrian official news agency SANA, shows smoke rising from burned cars after a huge explosion shook the Sabaa Bahrat Square, one of the capital's biggest roundabouts, in Damascus, Syria, Monday, April. 8, 2013. A car bomb rocked a busy residential and commercial district in central Damascus on Monday, killing more than a dozen with many more injured and sending a huge cloud of black smoke billowing over the capital?s skyline, Syrian state-run media said. (AP Photo/SANA)
DAMASCUS, Syria (AP) ? A suicide bomber detonated his explosives-packed vehicle in a busy residential and commercial district in central Damascus on Monday, killing at least 15 people and sending a huge cloud of black smoke billowing over the capital's skyline, Syrian state-run media said.
The explosion came as U.N. chief Ban Ki-moon said inspectors were ready to deploy within 24 hours to Syria to investigate reports of chemical weapon attacks but have not yet received permission from President Bashar Assad's government.
Monday's blast, described by state-run Syrian TV as a terrorist suicide bombing, went off near the Sabaa Bahrat Square, one of the capital's biggest roundabouts. The Syrian central bank, the Finance Ministry and state-run investment agency, a mosque and a school are located nearby.
The explosion also wounded at least 53 people, according to Syrian state TV.
It was the latest in a series of car bombs and suicide bombings to hit the Syrian capital in recent months. The two-year civil war, which the U.N. says has killed more than 70,000 people, has become increasingly chaotic as rebels press closer to Assad's seat of power in Damascus after seizing large swaths of territory in the northern and eastern parts of the country.
TV images showed thick black smoke billowing in a wide street with several cars on fire. At least six bodies were seen lying on the pavement. Paramedics carried a young woman lying on a stretcher, her face bloodied, into an ambulance.
Shaken teenage students holding their backpacks were seen walking away. The TV said the blast occurred near the Bukhari School.
Among the buildings damaged was the state-run Syrian Investment Agency. Several cars in the building's parking lot were set ablaze in the explosion. Witnesses said a suicide attacker tried to storm the building with his vehicle but was stopped by guards. He then detonated his explosives outside the building.
"I was in the square when I heard a strong explosion that threw me on the ground," said civil servant Hussein Khalil, 32. "I ran and saw what happened," he told The Associated Press at the scene of the explosion.
Electrician Mohammed Ali Kheir, 21, said he was nearby and felt the pressure of the blast. "I immediately ran here and helped paramedics evacuate four wounded people," he told AP.
"Is this the freedom that Qatar and Saudi Arabia want," asked the man, referring to the Gulf Arab countries that have backed Syrian rebels fighting to remove Assad from power.
In the footage by Syrian TV, one woman shouted sarcastically: "Thank you, Hamad, is this what you want?" She was referring to the emir of Qatar, a major rebel supporter.
Assad's regime denies there is a popular uprising and refers to the rebels as "terrorists" and "mercenaries," allegedly backed by foreign powers trying to destabilize the country.
According to the TV footage, the dead included a young man whose face was blown off by the force of the blast. Shortly after, another man is seen covering the victim's head with his T-shirt.
Nearby, several men are seen twisting the wreckage of a car, trying to rescue a man who appears motionless in the back seat of a car.
Fire fighters struggled to extinguish flames that engulfed the two buildings near the site of the explosion as well as a row of cars near the roundabout.
The last large explosion in central Damascus was on Feb. 21, just a few blocks away from Monday's site, when a suicide car bombing near the ruling Baath Party headquarters killed 53 people and wounded more than 200, according to state media.
Anti-regime activists at the time put the death toll at 61, which would make it the deadliest bombing in the capital in the two-year Syrian civil war.
Last month, a suicide bomb ripped through a mosque in the heart of the capital, killing a top Sunni Muslim preacher and outspoken supporter of Assad and 41 others in one of the most stunning assassinations of the war.
There was no claim of responsibility for those two Damascus attacks and there was no immediate claim for Monday's blast.
In the past, the Islamic militant group Jabhat al-Nusra, an al-Qaida-affiliated group, which the U.S. has designated as a terrorist organization has claimed responsibility for some of the deadliest suicide bombings targeting regime and military facilities across the country.
The violence has shattered the sense of normalcy that the Syrian regime has desperately tried to maintain in Damascus, a city that was until recently mostly insulated from the bloodshed and destruction that has left other urban centers in ruins.
The anti-Assad rebels launched an offensive on Damascus in July after a stunning bombing on a high-level government crisis meeting that killed four top regime officials, including Assad's brother-in-law and the defense minister. Following that attack, rebel groups that had established footholds in the suburbs pushed in, battling government forces for more than a week before being routed and swept out.
Since then, government warplanes have pounded opposition strongholds on the outskirts, and rebels have managed only small incursions on the city's southern and eastern sides. More recently, they have taken to firing deadly mortar shells deep into the capital as way to loosen the regime's grip on power.
Assad's government has asked the U.N. chief to investigate an alleged chemical weapons attack by rebels on March 19 on a village in northern Syria. Both the rebels and the regime traded blame for the alleged attack, which has not been confirmed.
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Associated Press writer Mike Corder contributed to this report from The Hague.
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